Particulate bioactive glass has been used as a bone graft material for the filling of osseous defects since 1994.  Good tissue healing and a lack of infections noted with its use in oral periodontal studies suggested an antibacterial effect for this material.

Unlike steel or other implants, Bioglass® (PerioGlas®, NovaBone® and NovaBone-C/M®) is not rejected. In fact, Bioglass® slowly releases small amounts of soluble silica and calcium, which in turn activate seven families of genes present in bone cells, causing them to create new, healthy bone.

Particulate bioactive glass has been used as a bone graft material for the filling of osseous defects since 1994. Good tissue healing and a lack of infections noted with its use in oral periodontal studies suggested an antibacterial effect for this material. Recent in vitro studies have evaluated bioactive glass for its effect on various oral bacteria and was found to exert an antibacterial effect against all bacterial strains against which it was tested.

The use of Bioglass® synthetic graft devices reduces the surgical costs and risks associated with the harvesting of autogenous tissues. These devices are produced to set specifications to control any differences between batches, resulting in a safe and effective product. To date, over 850,000 particulate Bioglass® devices have been produced and sold for the treatment of osseous defects around the world.

A recent development in the bone graft field include devices with various proteins, either alone or as adjuncts to current graft materials, to stimulate and increase bone formation in a grafted defect. While a few such devices are clinically available, little justification in terms of end results has been provided for the 2-to 3-fold increase in protein device cost.

  Safe

Bioactive Glass has been used as a bone graft material for over a decade. It has been used in over 850,000 medical/dental applications. Bioactive glass has a long standing proven record of safety and efficacy.